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Boosting oral surgery with REGENFAST®

Regenerative treatment of a site after osteonecrosis of the jaw

Dr. Alberto Pispero · Italy
 · December 12, 2023
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"I used REGENFAST® for the healing of the surgical site. Polynucleotides and hyaluronic acid seem to speed up soft-tissue healing. This is essential for improved bone healing in patients at risk of medication-related osteonecrosis of the jaw."

The Situation

Following the extraction of tooth 42, a drug-induced osteonecrosis was diagnosed and treated. One week after the treatment, the clinical picture had improved and the symptoms were significantly reduced.


Approach & Result

1 | Cone beam sections show a fragment of necrotic bone.
1 | Cone beam sections show a fragment of necrotic bone.
2 | Fistula in relation to the edentulous crest through which the bone crest can be probed.
2 | Fistula in relation to the edentulous crest through which the bone crest can be probed.
3 | Intraoperative image of the necrotic bone fragment, corresponding to the vestibular cortex of the element previously extracted.
3 | Intraoperative image of the necrotic bone fragment, corresponding to the vestibular cortex of the element previously extracted.
4 | The removal of the fragment is simple because of complete sequestration.
4 | The removal of the fragment is simple because of complete sequestration.
5 | The clinically healthy bone tissue is curetted and a generous layer of REGENFAST® is applied before wound closure by primary intention.
5 | The clinically healthy bone tissue is curetted and a generous layer of REGENFAST® is applied before wound closure by primary intention.
6 | The viscosity of the product allows it to remain in the intervention site. Contact with saliva would cause rapid dispersion in the oral cavity.
6 | The viscosity of the product allows it to remain in the intervention site. Contact with saliva would cause rapid dispersion in the oral cavity.
7 | After the suture, the excess part of the product is applied on the suture line.
7 | After the suture, the excess part of the product is applied on the suture line.
8 | Perfectly healthy tissues with no signs of pathology three months after the surgery.
8 | Perfectly healthy tissues with no signs of pathology three months after the surgery.
9 | The intraoral radiographic image confirms the bone healing of the treated site.
9 | The intraoral radiographic image confirms the bone healing of the treated site.
1 | Cone beam sections show a fragment of necrotic bone.
2 | Fistula in relation to the edentulous crest through which the bone crest can be probed.
3 | Intraoperative image of the necrotic bone fragment, corresponding to the vestibular cortex of the element previously extracted.
4 | The removal of the fragment is simple because of complete sequestration.
5 | The clinically healthy bone tissue is curetted and a generous layer of REGENFAST® is applied before wound closure by primary intention.
6 | The viscosity of the product allows it to remain in the intervention site. Contact with saliva would cause rapid dispersion in the oral cavity.
7 | After the suture, the excess part of the product is applied on the suture line.
8 | Perfectly healthy tissues with no signs of pathology three months after the surgery.
9 | The intraoral radiographic image confirms the bone healing of the treated site.

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About the author

Dr. Alberto Pispero | Italy

Oral surgeon, Milan, Italy

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